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Image Search Results
Journal: Journal of neurochemistry
Article Title: Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat.
doi: 10.1046/j.1471-4159.2001.00541.x
Figure Lengend Snippet: Fig. 2 Changes in plasma concentration of the OX26 and Ni-IgG2a with time after injection expressed as % ID/mL plasma ^ SD in adult (a) and P15 (b) rats. Initially, the concentration of OX26 decreases markedly to a signi®cantly lower concentration than Ni-IgG2a, and from 2 min and onwards, the plasma concentration of OX26 and Ni-IgG2a are statistically different at any time point. The diamonds marked by an arrow represent the corresponding values of OX26 and Ni-IgG2a (identical colour) of iron-de®cient P15 rats; these values are not statistically different to the corresponding values of P15 rats having a normal iron status. Each value is the mean ^ SD of measurements from 3 to 5 rats. A, OX26; B, Ni-Ig2a.
Article Snippet: Puri®ed monoclonal mouse-anti-rat transferrin receptor IgG2a (clone OX26) and
Techniques: Clinical Proteomics, Concentration Assay, Injection
Journal: Journal of neurochemistry
Article Title: Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat.
doi: 10.1046/j.1471-4159.2001.00541.x
Figure Lengend Snippet: Fig. 3 Accumulation of OX26 and Ni-IgG2a expressed as % ID/organ ^ SD in adult brain (a) and adult liver (b). The accumu- lation of both OX26 and Ni-IgG2a is much higher in the liver than in the brain (*). At 60 min, the accumulation of OX26 in the brain is signi®cantly higher than at 30 min post-injection. A, OX26; B, Ni-Ig2a.
Article Snippet: Puri®ed monoclonal mouse-anti-rat transferrin receptor IgG2a (clone OX26) and
Techniques: Injection
Journal: Journal of neurochemistry
Article Title: Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat.
doi: 10.1046/j.1471-4159.2001.00541.x
Figure Lengend Snippet: Fig. 6 Accumulation of OX26 and Ni-IgG2a in CSF of adult and P15 rats expressed as % ID/mL CSF 1 SD (a) or Vd expressed as mL plasma/mL CSF 1 SD (b). (a) The uptake of both proteins are signi®cantly higher in the P15 rat than in the adult (*). OX26 accu- mulates to a signi®cantly higher degree than Ni-IgG2a in both the adult and P15 rat (o). (b) When expressed in terms of Vd, OX26 accumulation is greater than Ni-IgG2a at both ages (o). The Vd values of OX26 and Ni-IgG2a are not statistically different.
Article Snippet: Puri®ed monoclonal mouse-anti-rat transferrin receptor IgG2a (clone OX26) and
Techniques: Clinical Proteomics